We formulate the Riemannian calculus of the probability set embedded with L^2-Wasserstein metric. This is an initial work of transport information geometry. Our investigation starts with the probability simplex (probability manifold) supported on vertices of a finite graph. The main idea is to embed the probability manifold as a submanifold of the positive measure space with a nonlinear metric tensor. Here the nonlinearity comes from the linear weighted Laplacian operator. By this viewpoint, we establish torsion-free Christoffel symbols, Levi-Civita connections, curvature tensors, and volume forms in the probability manifold by Euclidean coordinates. As a consequence, the Jacobi equation, Laplace-Beltrami and Hessian operators on the probability manifold are derived. These geometric computations are also provided in the infinite-dimensional density space (density manifold) supported on a finite-dimensional manifold. In particular, an identity is given connecting the Baker-{É}mery Γ2 operator (carr{é} du champ it{é}r{é}) by connecting Fisher-Rao information metric and optimal transport metric. Several examples are demonstrated.

We explain how the classical notions of Fisher information of a random variable and Fisher information matrix of a random vector can be extended to a much broader setting. We also show that Stam’s inequality for Fisher information and Shannon entropy, as well as the more generalized versions proved earlier by the authors, are all special cases of more general sharp inequalities satisfied by random vectors. The extremal random vectors, which we call generalized Gaussians, contain Gaussians as a limiting case but are noteworthy because they are heavy- tailed.

A unified approach is presented for establishing a broad class of Cram\'er-Rao inequalities for the location parameter, including, as special cases, the original inequality of Cram\'er and Rao, as well as an $L^p$ version recently established by the authors. The new approach allows for generalized moments and Fisher information measures to be defined by convex functions that are not necessarily homogeneous. In particular, it is shown that associated with any log-concave random variable whose density satisfies certain boundary conditions is a Cram\'er-Rao inequality for which the given log-concave random variable is the extremal. Applications to specific instances are also provided.

Poisson equation on point cloud with Dirichlet boundary condition plays important role in many problems. In this paper, we use the volume constraint proposed by Du et.al to handle the Dirichlet boundary condition in the point integral method for Poisson equation on point cloud. We prove that the solution given by volume constraint converges to the true solution as the point cloud converges to the underlying smooth manifold.

For a random quantum state on $\cH=\C^d \otimes \C^d$ obtained by partial tracing a random pure state on $\cH \otimes \C^s$, we consider the question whether it is typically separable or typically entangled. For this problem, we show the existence of a sharp threshold $s_0=s_0(d)$ of order roughly $d^3$. More precisely, for any $\e>0$ and for $d$ large enough, such a random state is entangled with very large probability when $s \leq (1-\e)s_0$, and separable with very large probability when $s \geq (1+\e) s_0$. One consequence of this result is as follows: for a system of $N$ identical particles in a random pure state, there is a threshold $k_0 = k_0(N)\sim N/5$ such that two subsystems of $k$ particles each typically share entanglement if $k>k_0$, and typically do not share entanglement if $k<k_0$. Our methods work also for multipartite systems and for ``unbalanced'' systems such as $\C^{d_1} \otimes \C^{d_2} $, ${d_1} \neq {d_2} $. The arguments rely on random matrices, classical convexity, high-dimensional probability and geometry of Banach spaces; some of the auxiliary results may be of reference value.