The purpose of this paper is to propose methodologies for statistical inference of low dimensional parameters with high dimensional data.We focus on constructing confidence intervals for individual coefficients and linear combinations of several of them in a linear regression model, although our ideas are applicable in a much broader context.The theoretical results that are presented provide sufficient conditions for the asymptotic normality of the proposed estimators along with a consistent estimator for their finite dimensional covariance matrices. These sufficient conditions allow the number of variables to exceed the sample size and the presence of many small non-zero coefficients. Our methods and theory apply to interval estimation of a preconceived regression coefficient or contrast as well as simultaneous interval estimation of many regression coefficients. Moreover, the method proposed turns the regression data into an approximate Gaussian sequence of point estimators of individual regression coefficients, which can be used to select variables after proper thresholding. The simulation results that are presented demonstrate the accuracy of the coverage probability of the confidence intervals proposed as well as other desirable properties, strongly supporting the theoretical results.

We propose a deep learning-based method for object detection in UAV-borne thermal images that have the capability of observing scenes in both day and night. Compared with visible images, thermal images have lower requirements for illumination conditions, but they typically have blurred edges and low contrast. Using a boundary-aware salient object detection network, we extract the saliency maps of the thermal images to improve the distinguishability. Thermal images are augmented with the corresponding saliency maps through channel replacement and pixel-level weighted fusion methods. Considering the limited computing power of UAV platforms, a lightweight combinational neural network ComNet is used as the core object detection method. The YOLOv3 model trained on the original images is used as a benchmark and compared with the proposed method. In the experiments, we analyze the detection performances of the ComNet models with different image fusion schemes. The experimental results show that the average precisions (APs) for pedestrian and vehicle detection have been improved by 2%~5% compared with the benchmark without saliency map fusion and MobileNetv2. The detection speed is increased by over 50%, while the model size is reduced by 58%. The results demonstrate that the proposed method provides a compromise model, which has application potential in UAV-borne detection tasks.

We demonstrate how path integrals often used in problems of theoretical physics can be adapted to provide a machinery for performing Bayesian inference in function spaces. Such inference comes about naturally in the study of inverse problems of recovering continuous (infinite dimensional) coefficient functions from ordinary or partial differential equations, a problem which is typically ill-posed. Regularization of these problems using L2 function spaces (Tikhonov regularization) is equivalent to Bayesian probabilistic inference, using a Gaussian prior. The Bayesian interpretation of inverse problem regularization is useful since it allows one to quantify and characterize error and degree of precision in the solution of inverse problems, as well as examine assumptions made in solving the problem—namely whether the subjective choice of regularization is compatible with prior knowledge. Using path-integral formalism, Bayesian inference can be explored through various perturbative techniques, such as the semiclassical approximation, which we use in this manuscript. Perturbative path-integral approaches, while offering alternatives to computational approaches like Markov-Chain-Monte-Carlo (MCMC), also provide natural starting points for MCMC methods that can be used to refine approximations. In this manuscript, we illustrate a path-integral formulation for inverse problems and demonstrate it on an inverse problem in membrane biophysics as well as inverse problems in potential theories involving the Poisson equation.