Quotient sets have attracted the attention of mathe- maticians in the past three decades. The set of quotients of primes is dense in the positive real numbers and the set of all quotients of Gauss- ian primes is also dense in the complex plane. Sittinger has proved that the set of quotients of primes in an imaginary quadratic ring is dense in the complex plane and the set of quotients of primes in a real quadratic number ring is dense in R: An interesting open question is introduced by Sittinger: Is the set of quotients of Hurwitz primes dense in the quaternions? In this paper, we answer the question and prove that the set of all quotients of Hurwitz primes is dense in the quaternions.

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The problem of the existence of infinitely many prime values of a number-theoretic function f (x) has been one of the most important topics in Number Theory. Note that if f (x) represents infinitely many primes, then we can get this necessary condition: for any positive integer h , there exists a positive integer k such that ( f (k), h) =1and f (k) >1. Naturally, we are interested in the number-theoretic functions f (x) that satisfy the aforementioned necessary condition. Thus, there must exist the least positive integer n such that (f(n),h)-1andf(k)>1. Denote this least positive integer n byF_f(h). In this paper, we mainly focus on three famous number-theoretic functions:&f(x)=2^{2^x}+1,m(x)=2^x-1 and l(x)=x^2+1& proving they satisfy the aforementioned necessary condition respectively. Furthermore, we approximately estimate the upper bound of F_f(x)(h),Fm(x)(h)，Fl(x)(h) respectively, and obtain some interesting results.