Let g(t) be a smooth complete solution to the Ricci flow on a noncompact manifold such that g(0) is Kahler. We prove that if |Rm(g(t))| is bounded by a/t for some a > 0, then g(t) is Kahler for t > 0. We prove that there is a constant a(n) > 0 depending only on n such that the following is true: Suppose g(t) is a smooth complete solution to the Kahler-Ricci flow on a non-compact n-dimensional complex manifold such that g(0) has nonnegative holomorphic bisectional curvature and |Rm(g(t))| ≤ a(n)/t, then g(t) has nonnegative holomorphic bisectional curvature for t > 0. These generalize the results by Wan-Xiong Shi. As applications, we prove that (i) any complete noncompact Kahler manifold with nonnegative complex sectional curvature and maximum volume growth is biholomorphic to C^n; and (ii) there is ε(n) > 0 depending only on n such that if (M^n,g_0) is a complete noncompact Kahler manifold of complex dimension n with nonnegative holomorphic bisectional curvature and maximum volume growth and if (1+ε(n))^{−1}h ≤ g_0 ≤ (1+ε(n))h for some Riemannian metric h with bounded curvature, then M is biholomorphic to C^n.