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There is gained interest in understanding statistical inference under possibly non-sparse high-dimensional models. For a given component of the regression coefficient, we show that the difficulty of the problem depends on the sparsity of the corresponding row of the precision matrix of the covariates, not the sparsity of the regression coefficients. We develop new concepts of uniform and essentially uniform non-testability that allow the study of limitations of tests across a broad set of alternatives. Uniform non-testability identifies a collection of alternatives such that the power of any test, against any alternative in the group, is asymptotically at most equal to the nominal size of the test. Implications of the new constructions include new minimax testability results that in sharp contrast to the existing results, do not depend on the sparsity of the regression parameters. We identify new tradeoffs between testability and feature correlation. In particular, we show that in models with weak feature correlations minimax lower bound can be attained by a test whose power has the parametric rate regardless of the size of the model sparsity.

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Prediction error is critical to assessing the performance of statistical methods and selecting statistical models. We propose the cross-validation and approximated cross-validation methods for estimating prediction error under a broad q-class of Bregman divergence for error measures which embeds nearly all of the commonly used loss functions in regression, classification procedures and machine learning literature. The approximated cross-validation formulas are analytically derived, which facilitate fast estimation of prediction error under the Bregman divergence. We then study a data-driven optimal bandwidth selector for the local-likelihood estimation that minimizes the overall prediction error or equivalently the covariance penalty. It is shown that the covariance penalty and cross-validation methods converge to the same mean-prediction-error-criterion. We also propose a lower-bound scheme for computing the local logistic regression estimates and demonstrate that it is as simple and stable as the local least-squares regression estimation. The algorithm monotonically enhances the target local-likelihood and converges. The idea and methods are extended to the generalized varying-coefficient models and semiparametric models.

1. Introduction. 1.1. Background. Covariance matrix estimation is fundamental for almost all areas of multivariate analysis and many other applied problems. In particular, covariance matrices and their inverses play a central role in risk management and portfolio allocation. For example, the smallest and largest eigenvalues are related to the minimum and maximum variances of the selected portfolio, respectively, and the eigenvectors are related to portfolio allocation. Therefore, we need a good covariance matrix estimator that is well-conditioned, ie inverting it does not excessively amplify the estimation error. See Goldfarb and Iyengar (2003) for applications of covariance matrices to portfolio selections and Johnstone (2001) for their statistical implications. Estimating large dimensional covariance matrices is intrinsically challenging. For example, in portfolio allocation and risk management, the number p of stocks can

Value at Risk is a fundamental tool for managing market risks. It measures the worst loss to be expected of a portfolio over a given time horizon under normal market conditions at a given confidence level. Calculation of VaR frequently involves estimating the volatility of return processes and quantiles of standardized returns. In this paper, several semiparametric techniques are introduced to estimate the volatilities of the market prices of a portfolio. In addition, both parametric and nonparametric techniques are proposed to estimate the quantiles of standardized return processes. The newly proposed techniques also have the flexibility to adapt automatically to the changes in the dynamics of market prices over time. Their statistical efficiencies are studied both theoretically and empirically. The combination of newly proposed techniques for estimating volatility and standardized quantiles yields several new techniques for forecasting multiple period VaR. The performance of the newly proposed VaR estimators is evaluated and compared with some of existing methods. Our simulation results and empirical studies endorse the newly proposed time-dependent semiparametric approach for estimating VaR.

Two measures of sensitivity to initial conditions in nonlinear time series are proposed. The notions give some insight into the relationship between the Fisher information in statistical estimation and initial-value sensitivity in dynamical systems. By using the locally polynomial regression, we develop nonparametric estimates for a conditional density function, its square root and its partial derivatives. The proposed procedures are innovative and of interests in their own right. They are also used to estimate the sensitive measures. The asymptotic normality of the proposed estimators have been proved. We also propose a simple and intuitively appealing method for choosing the bandwidths. Two simulated examples are used as illustrations.

Several novel large volatility matrix estimation methods have been developed based on the high-frequency financial data. They often employ the approximate factor model that leads to a low-rank plus sparse structure for the integrated volatility matrix and facilitates estimation of large volatility matrices. However, for predicting future volatility matrices, these nonparametric estimators do not have a dynamic structure to implement. In this paper, we introduce a novel It diffusion process based on the approximate factor models and call it a factor GARCH-It model. We then investigate its properties and propose a quasi-maximum likelihood estimation method for the parameter of the factor GARCH-It model. We also apply it to estimating conditional expected large volatility matrices and establish their asymptotic properties. Simulation studies are conducted to validate the finite sample performance of the proposed

We propose a bootstrap-based robust high-confidence level upper bound (Robust H-CLUB) for assessing the risks of large portfolios. The proposed approach exploits rank-based and quantile-based estimators, and can be viewed as a robust extension of the H-CLUB procedure (Fan etal., 2015). Such an extension allows us to handle possibly misspecified models and heavy-tailed data, which are stylized features in financial returns. Under mixing conditions, we analyze the proposed approach and demonstrate its advantage over H-CLUB. We further provide thorough numerical results to back up the developed theory, and also apply the proposed method to analyze a stock market dataset.

Motivated by the problem of colocalization analysis in fluorescence microscopic imaging, we study in this paper structured detection of correlated regions between two random processes observed on a common domain. We argue that although intuitive, direct use of the maximum log-likelihood statistic suffers from potential bias and substantially reduced power, and introduce a simple size-based normalization to overcome this problem. We show that scanning with the proposed size-corrected likelihood ratio statistics leads to optimal correlation detection over a large collection of structured correlation detection problems.

In event studies of capital market efficiency, an earnings surprise has historically been measured by the consensus error, defined as earnings minus the consensus or average of professional forecasts. The rationale is that the consensus is an accurate measure of the markets expectation of earnings. But since forecasts can be biased due to conflicts of interest and some investors can see through these conflicts, this rationale is flawed and the consensus error a biased measure of an earnings surprise. We show that the fraction of forecasts that miss on the same side (FOM), by ignoring the size of the misses, is less sensitive to such bias and a better measure of an earnings surprise. As a result, FOM out-performs the consensus error and its related robust statistics in explaining stock price movements around and subsequent to the announcement date.