Here we propose a novel method to compute Teichmller shape space based shape index to study brain morphometry. Such a shape index is intrinsic, and invariant under conformal transformations, rigid motions and scaling. We conformally map a genus-zero open boundary surface to the Poincar disk with the Yamabe flow method. The shape indices that we compute are the lengths of a special set of geodesics under hyperbolic metric. Tests on longitudinal brain imaging data were used to demonstrate the stability of the derived feature vectors. In leave-one-out validation tests, we achieved 100% accurate classification (versus only 68% accuracy for volume measures) in distinguishing 11 HIV/AIDS individuals from 8 healthy control subjects, based on Teichmller coordinates for lateral ventricular surfaces extracted from their 3D MRI scans.

We study the generalized eigenvalue problems (GEPs) derived from modeling the surface acoustic wave in piezoelectric materials with periodic inhomogeneity. The eigenvalues appear in the reciprocal pairs due to periodic boundary conditions in the modeling. By transforming the GEP into a T-palindromic quadratic eigenvalue problem (TPQEP), the reciprocal relationship of the eigenvalues can be maintained. In this paper, we outline four recently developed structure-preserving algorithms, SA, SDA, TSHIRA and GTSHIRA, for solving the TPQEP. Numerical comparisons on the accuracy and the computational costs of these algorithm are presented. The eigenvalues close to unit circle on the complex plane are of interest in the area of filter and sensor designs. Our numerical results show that the Arnoldi-type structure-preserving algorithms TSHIRA and GTSHIRA with re-symplectic and re-bi-isotropic processes

We study a class of nonlinear nonlocal cochlear models of the transmission line type, describing the motion of basilar membrane (BM) in the cochlea. They are damped dispersive partial differential equations (PDEs) driven by time dependent boundary forcing due to the input sounds. The global well-posedness in time follows from energy estimates. Uniform bounds of solutions hold in the case of bounded nonlinear damping. When the input sounds are multi-frequency tones, and the nonlinearity in the PDEs is cubic, we construct smooth quasi-periodic solutions (multi-tone solutions) in the weakly nonlinear regime, where new frequencies are generated due to nonlinear interaction. When the input consists of two tones at frequencies f 1, f 2 (f 1< f 2), and high enough intensities, numerical results illustrate the formation of combination tones at 2f 1 f 2 and 2f 2 f 1, in agreement with hearing experiments. We visualize

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