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We establish an analytic interpretation for the index of certain transversally elliptic symbols on non-compact manifolds. By using this interpretation, we establish a geometric quantization formula for a Hamiltonian action of a compact Lie group acting on a non-compact symplectic manifold with proper moment map. In particular, we present a solution to a conjecture of Michèle Vergne in her ICM 2006 plenary lecture.

We show that the transition probability of the Markov chain ($G$($i$,1),...,$G$($i$,$n$))_{$i$≥1}, where the$G$($i$,$j$)’s are certain directed last-passage times, is given by a determinant of a special form. An analogous formula has recently been obtained by Warren in a Brownian motion model. Furthermore we demonstrate that this formula leads to the Meixner ensemble when we compute the distribution function for$G$($m$,$n$). We also obtain the Fredholm determinant representation of this distribution, where the kernel has a double contour integral representation.

For smooth compact oriented Riemannian manifolds$M$of dimension 4$k$+2,$k$≥0, with or without boundary, and a vector bundle$F$on$M$with an inner product and a flat connection, we construct a modification of the Hodge star operator on the middle-dimensional (parabolic) cohomology of$M$twisted by$F$. This operator induces a canonical complex structure on the middle-dimensional cohomology space that is compatible with the natural symplectic form given by integrating the wedge product. In particular, when$k$=0 we get a canonical almost complex structure on the non-singular part of the moduli space of flat connections on a Riemann surface, with monodromies along boundary components belonging to fixed conjugacy classes when the surface has boundary, that is compatible with the standard symplectic form on the moduli space.