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We determine all helix surfaces with parallel mean curvature vector field which are not minimal or pseudo-umbilical in spaces of type $M^{n}(c)\times\mathbb{R}$ , where$M$^{$n$}($c$) is a simply connected$n$-dimensional manifold with constant sectional curvature$c$.

Macrophages play an important role in the inflammatory responses involved with spinal cord injury (SCI). We have previously demonstrated that infiltrated bone marrow-derived macrophages (BMDMs) engulf myelin debris, forming myelin-laden macrophages (mye-M). These mye-M promote disease progression through their pro-inflammatory phenotype, enhanced neurotoxicity, and impaired phagocytic capacity for apoptotic cells. We thus hypothesize that the excessive accumulation of mye-M is the root of secondary injury, and that targeting mye-M represents an efficient strategy to improve the local inflammatory microenvironment in injured spinal cords and to further motor neuron function recovery. In this study, we administer murine embryonic stem cell conditioned media (ESC-M) as a cell-free stem cell based therapy to treat a mouse model of SCI. We showed that BMDMs, but not microglial cells, engulf myelin debris generated at the injury site. Phagocytosis of myelin debris leads to the formation of mye-M in the injured spinal cord, which are surrounded by activated microglia cells. These mye-M are pro-inflammatory and lose the normal macrophage phagocytic capacity for apoptotic cells. We therefore focus on how to trigger lipid efflux from mye-M and thus restore their function. Using ESC-M as an immune modulating treatment for inflammatory damage after SCI, we rescued mye-M function and improved functional locomotor recovery. ESC-M treatment on mye-M resulted in improved exocytosis of internalized lipids and a normal capacity for apoptotic cell phagocytosis. Furthermore, when ESC-M was administered

In this paper we generalize a result in [J. An, Z. Wang, On the realization of Riemannian symmetric spaces in Lie groups, Topology Appl. 153 (7) (2005) 10081015, showing that an arbitrary Riemannian symmetric space can be realized as a closed submanifold of a covering group of the Lie group defining the symmetric space. Some properties of the subgroups of fixed points of involutions are also proved.

In the present paper we extend the Riemann–Roch formalism to structure algebras of moment graphs. We introduce and study the Chern character and push-forwards for twisted fibrations of moment graphs. We prove an analogue of the Riemann–Roch theorem for moment graphs. As an application, we obtain the Riemann–Roch type theorem for the equivariant K‑theory of some Kac–Moody flag varieties.