We show that Q-Fano varieties of fixed dimension with anti-canonical degrees and alpha-invariants bounded from below form a bounded family. As a corollary, K-semistable Q-Fano varieties of fixed dimension with anti-canonical degrees bounded from below form a bounded family.

Generalizing the continuous rank function of Barja-Pardini-Stoppino, in this paper we consider cohomological rank functions of Q-twisted (complexes of) coherent sheaves on abelian varieties. They satisfy a natural transformation formula with respect to the Fourier-Mukai-Poincar´e transform, which has several consequences. In many concrete geometric contexts these functions provide useful invariants. We illustrate this with two different applications, the first one to GVsubschemes and the second one to multiplication maps of global sections of ample line bundles on abelian varieties.

In this paper, the first in a series, we study the deformed Hermitian-Yang-Mills (dHYM) equation from the variational point of view as an infinite dimensional GIT problem. The dHYM equation is mirror to the special Lagrangian equation, and our infinite dimensional GIT problem is mirror to Thomas' GIT picture for special Lagrangians. This gives rise to infinite dimensional manifold $\mathcal{H}$ closely related to Solomon's space of positive Lagrangians. In the hypercritical phase case we prove the existence of smooth approximate geodesics, and weak geodesics with $C^{1,\alpha}$ regularity. This is accomplished by proving sharp with respect to scale estimates for the Lagrangian phase operator on collapsing manifolds with boundary. As an application of our techniques we give a simplified proof of Chen's theorem on the existence of $C^{1,\alpha}$ geodesics in the space of K\"ahler metrics. In two follow up papers, these results will be used to examine algebraic obstructions to the existence of solutions to dHYM and special Lagrangians in Landau-Ginzburg models.

The stochasticity of gene expression is manifested in the fluctuations of mRNA and protein copy numbers within a cell lineage over time. While data of this type can be obtained for many generations, most mathematical models are unsuitable to interpret such data since they assume non-growing cells. Here we develop a theoretical approach that quantitatively links the frequency content of lineage data to subcellular dynamics. We elucidate how the position, height, and width of the peaks in the power spectrum provide a distinctive fingerprint that encodes a wealth of information about mechanisms controlling transcription, translation, replication, degradation, bursting, promoter switching, cell cycle duration, cell division, gene dosage compensation, and cell size homeostasis. Predictions are confirmed by analysis of single-cell Escherichia coli data obtained using fluorescence microscopy. Furthermore, by matching the experimental and theoretical power spectra, we infer the temperature-dependent gene expression parameters, without the need of measurements relating fluorescence intensities to molecule numbers.

We present an integral representation for the tensor product L-function of a pair of automorphic cuspidal representations, one of a classical group, the other of a general linear group. Our construction is uniform over all classical groups, and is applicable to all cuspidal representations; it does not require genericity. The main new ideas of the construction are the use of generalized Speh representations as inducing data for the Eisenstein series and the introduction of a new (global and local) model, which generalizes the Whittaker model. Here we consider linear groups, but our construction also extends to arbitrary degree metaplectic coverings; this will be the topic of an upcoming work.