Big Data bring new opportunities to modern society and challenges to data scientists. On the one hand, Big Data hold great promises for discovering subtle population patterns and heterogeneities that are not possible with small-scale data. On the other hand, the massive sample size and high dimensionality of Big Data introduce unique computational and statistical challenges, including scalability and storage bottleneck, noise accumulation, spurious correlation, incidental endogeneity and measurement errors. These challenges are distinguished and require new computational and statistical paradigm. This paper gives overviews on the salient features of Big Data and how these features impact on paradigm change on statistical and computational methods as well as computing architectures. We also provide various new perspectives on the Big Data analysis and computation. In particular, we emphasize on

Let $\Omega $ be a bounded $C^2$ domain in $R^n$ and $\phi : \partial \Omega \to \mathbb{R}^m$ be a continuous map. The Dirichlet problem for the minimal surface system asks whether there exists a Lipschitz map $f : \Omega \to \mathbb{R}^m$ with $ f |_{\partial \Omega}$ and with the graph of $f$ a minimal submanifold in $R^{n+m}$. For $m = 1$, the Dirichlet problem was solved more than thirty years ago by Jenkins-Serrin [13] for any mean convex domains and the solutions are all smooth. This paper considers the Dirichlet problem for convex domains in arbitrary codimension $m$. We prove if $\psi : \bar{\Omega} \to \mathbb{R}^m$ satisfies $8n\delta sup_{\Omega}||D^2 \psi| + \sqrt{2} sup_{\partial \Omega} |D\psi| <1$, then the Dirichlet problem for $ \psi |_{\partial \Omega}$ is solvable in smooth maps. Here $\delta$ is the diameter of $\Omega$ . Such a condition is necessary in view of an example of Lawson-Osserman [15]. In order to prove this result, we study the associated parabolic system and solve the Cauchy-Dirichlet problem with $\psi$ as initial data.

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In this article, we classify all standard invariants that can arise from a composed inclusion of an A 3 with an A 4 subfactor. More precisely, if N P is an A 3 subfactor and P M is an A 4 subfactor, then only four standard invariants can arise from the composed inclusion N M. We answer a question posed by Bisch and Haagerup in 1994. The techniques of this paper also show that there are exactly four standard invariants for the composed inclusion of two A 4 subfactors.