Let$R$be a Noetherian ring, $\mathfrak{a}$ an ideal of$R$,$M$an$R$-module and$n$a non-negative integer. In this paper we first study the finiteness properties of the kernel and the cokernel of the natural map $f\colon\operatorname{Ext}^{n}_{R}(R/\mathfrak{a},M)\to \operatorname{Hom}_{R}(R/\mathfrak{a},\mathrm{H}^{n}_{\mathfrak{a}}(M))$ , under some conditions on the previous local cohomology modules. Then we get some corollaries about the associated primes and Artinianness of local cohomology modules. Finally we will study the asymptotic behavior of the kernel and the cokernel of the natural map in the graded case.