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We associate to any given finite set of valuations on the polynomial ring in two variables over an algebraically closed field a numerical invariant whose positivity characterizes the case when the intersection of their valuation rings has maximal transcendence degree over the base fields. As an application, we give a criterion for when an analytic branch at infinity in the affine plane that is defined over a number field in a suitable sense is the branch of an algebraic curve.

We prove the dynamical Mordell-Lang conjecture for birational polynomial morphisms on A^2.

Next-generation sequencing technology enables the routine detection of bacterial pathogens for clinical diagnostics and genetic research. Whole-genome sequencing has been of importance in the epidemiologic analysis of bacterial pathogens. However, few whole-genome sequencing-based genotyping pipelines are available for practical applications. Here, we present the whole-genome sequencing-based single nucleotide polymorphism(SNP) genotyping method and apply to the evolutionary analysis of methicillin-resistant Staphylococcus aureus. The SNP genotyping method calls genome variants using next-generation sequencing reads of whole genomes and calculates the pair-wise Jaccard distances of the genome variants. The method may reveal the high-resolution whole-genome SNP profiles and the structural variants of different isolates of methicillin-resistant S. aureus(MRSA) and methicillin-susceptible S. aureus(MSSA) strains. The phylogenetic analysis of whole genomes and particular regions may monitor and track the evolution and the transmission dynamic of bacterial pathogens. The computer pro- grams of the whole genome sequencing-based SNP genotyping methods are available to the public at https://github. com/ cyinbox/NGS.

In this paper, we propose a conjectural multiplicity formula for general spherical varieties. For all the cases where a multiplicity formula has been proved, including Whittaker model, Gan-Gross-Prasad model, Ginzburg-Rallis model, Galois model and Shalika model, we show that the multiplicity formula in our conjecture matches the multiplicity formula that has been proved. We also give a proof of this multiplicity formula in two new cases.