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In this paper, we build the unfolding approach from acyclic sign-skew-symmetric matrices of finite rank to skew-symmetric matrices of infinite rank, which can be regard as an improvement of that in the skew-symmetrizable case. Using this approach, we give a positive answer to the problem by Berenstein, Fomin and Zelevinsky in [6] which asks whether an acyclic signskew- symmetric matrix is always totally sign-skew-symmetric. As applications, the positivity for cluster algebras in acyclic sign-skew-symmetric case is given; further, the F-polynomials of cluster algebras are proved to have constant term 1 in acyclic sign-skew-symmetric case.

In this paper, we prove that, a compact complex manifold $X$ admits a smooth Hermitian metric with positive (resp., negative) scalar curvature if and only if $K_X$ (resp., $K_X^{-1}$) is not pseudo-effective. On the contrary, we also show that on an arbitrary compact complex manifold $X$ with complex dimension $\geq 2$, there exist smooth Hermitian metrics with positive total scalar curvature, and one of the key ingredients in the proof relies on a recent solution to the Gauduchon conjecture by G. Székelyhidi, V. Tosatti, and B. Weinkove.

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