Recently Freed and Hopkins [11] proved that there is no parity anomaly in M-theory on pin+ manifolds in the low-energy field theory approximation, and they also developed an algebraic theory of cubic forms. Earlier Witten [33] proved the anomaly cancellation for spin manifolds by introducing the E8-bundle technique. Motivated by the cubic forms and the anomaly cancellation formulas of Witten-Freed-Hopkins, we give some new cubic forms on spin, spinc, spinω2 and orientable 12- manifolds respectively. We relate them to η-invariants when the manifolds are with boundary, and mod 2 indices on 10 dimensional characteristic submanifolds when the manifolds are spinc or spinω2 . Our method of producing these cubic forms is a combination of (generalized) Witten classes and the character of the basic representation of affine E8.

We use entangled multimode coherent states to produce entangled giant graviton states, in the context of gauge/gravity duality. We make a smeared distribution of the entangled multimode coherent states on the circle, or on the five-sphere, in the higher dimensional view. In gauge/gravity duality, we analyze the superposition of giant graviton states, and the entangled pairs of giant graviton states. We map a class of angular distribution functions to unitary operations on the pairs. We also use Young tableau states to construct cat states and qudit states. Various bipartite quantum states involving Young tableau states are analyzed, including micro-macro entangled states. Mixed states of Young tableau states are generated, by using ensemble mixing using angular distribution functions, and also by going through noisy quantum channels. We then produce mixed entangled pair of giant graviton states, by including interaction with the environment and using noisy quantum channels.

We focus on two types of coherent states, the coherent states of multi graviton states and the coherent states of giant graviton states, in the context of gauge/gravity correspondence. We conveniently use a phase shift operator and its actions on the superpositions of these coherent states. We find N-state Schrodinger cat states which approach the one-row Young tableau states, with fidelity between them asymptotically reaches 1 at large N. The quantum Fisher information of these states is proportional to the variance of the excitation energy of the underlying states, and characterizes the localizability of the states in the angular direction in the phase space. We analyze the correlation and entanglement between gravitational degrees of freedom using different regions of the phase space plane in bubbling AdS. The correlation between two entangled rings in the phase space plane is related to the area of the annulus between the two rings. We also analyze two types of noisy coherent states, which can be viewed as interpolated states that interpolate between a pure coherent state in the noiseless limit and a maximally mixed state in the large noise limit.

The stochasticity of gene expression is manifested in the fluctuations of mRNA and protein copy numbers within a cell lineage over time. While data of this type can be obtained for many generations, most mathematical models are unsuitable to interpret such data since they assume non-growing cells. Here we develop a theoretical approach that quantitatively links the frequency content of lineage data to subcellular dynamics. We elucidate how the position, height, and width of the peaks in the power spectrum provide a distinctive fingerprint that encodes a wealth of information about mechanisms controlling transcription, translation, replication, degradation, bursting, promoter switching, cell cycle duration, cell division, gene dosage compensation, and cell size homeostasis. Predictions are confirmed by analysis of single-cell Escherichia coli data obtained using fluorescence microscopy. Furthermore, by matching the experimental and theoretical power spectra, we infer the temperature-dependent gene expression parameters, without the need of measurements relating fluorescence intensities to molecule numbers.

We study how conserved quantities such as angular momentum and center of mass evolve with respect to the retarded time at null infinity, which is described in terms of a Bondi-Sachs coordinate system. These evolution formulae complement the classical Bondi mass loss formula for gravitational radiation. They are further expressed in terms of the potentials of the shear and news tensors. The consequences that follow from these formulae are (1) Supertranslation invariance of the fluxes of the CWY conserved quantities. (2) A conservation law of angular momentum \`a la Christodoulou. (3) A duality paradigm for null infinity. In particular, the supertranslation invariance distinguishes the CWY angular momentum and center of mass from the classical definitions.