The approach combines second and fourth order statistics to perform BSS of instantaneous mixtures. It applies for any number of receivers if they are as many as sources. It is a batch algorithm that uses non-Gaussianity and stationarity of source signals. It is linear algebra based direct method, reliable and robust, though large dimensions of sources may slow down the computation significantly. It is however limited to instantaneous mixtures.

Local polynomial estimators are popular techniques for nonparametric regression estimation and have received great attention in the literature. Their simplest version, the local constant estimator, can be easily extended to the errors-in-variables context by exploiting its similarity with the deconvolution kernel density estimator. The generalization of the higher order versions of the estimator, however, is not straightforward and has remained an open problem for the last 15 years. We propose an innovative local polynomial estimator of any order in the errors-in-variables context, derive its design-adaptive asymptotic properties and study its finite sample performance on simulated examples. We provide not only a solution to a long-standing open problem, but also provide methodological contributions to error-in-variable regression, including local polynomial estimation of derivative functions.

The multiple testing procedure plays an important role in detecting the presence of spatial signals for large scale imaging data. Typically, the spatial signals are sparse but clustered. This paper provides empirical evidence that for a range of commonly used control levels, the conventional FDR procedure can lack the ability to detect statistical significance, even if the -values under the true null hypotheses are independent and uniformly distributed; more generally, ignoring the neighboring information of spatially structured data will tend to diminish the detection effectiveness of the FDR procedure. This paper first introduces a scalar quantity to characterize the extent to which the lack of identification phenomenon(LIP) of the FDR procedure occurs. Second, we propose a new multiple comparison procedure, called FDR, to accommodate the spatial information of neighboring -values, via a local aggregation of -values. Theoretical properties of the FDR procedure are investigated under weak dependence of -values. It is shown that the FDR procedure alleviates the LIP of the FDR procedure, thus substantially facilitating the selection of more stringent control levels. Simulation evaluations indicate that the FDR procedure improves the detection sensitivity of the FDR procedure with little loss in detection specificity. The computational simplicity and detection effectiveness of the FDR procedure are illustrated through a real brain fMRI dataset.

Improving efficiency for regression coefficients and predicting trajectories of individuals are two important aspects in the analysis of longitudinal data. Both involve estimation of the covariance function. Yet challenges arise in estimating the covariance function of longitudinal data collected at irregular time points. A class of semiparametric models for the covariance function by that imposes a parametric correlation structure while allowing a nonparametric variance function is proposed. A kernel estimator for estimating the nonparametric variance function is developed. Two methods for estimating parameters in the correlation structurea quasi-likelihood approach and a minimum generalized variance methodare proposed. A semiparametric varying coefficient partially linear model for longitudinal data is introduced, and an estimation procedure for model coefficients using a profile weighted least squares approach

Measuring conditional dependence is an important topic in statistics with broad applications including graphical models. Under a factor model setting, a new conditional dependence measure based on projection is proposed. The corresponding conditional independence test is developed with the asymptotic null distribution unveiled where the number of factors could be high-dimensional. It is also shown that the new test has control over the asymptotic significance level and can be calculated efficiently. A generic method for building dependency graphs without Gaussian assumption using the new test is elaborated. Numerical results and real data analysis show the superiority of the new method.