Discrepancy is a kind of important measure used in experimental design. Recently, a so-called discrete discrepancy has been applied to evaluate the uniformity of factorial designs. In this paper, we review some recent advances on application of the discrete discrepancy to several common experimental designs and summarize some important results.

Motivated by normalizing DNA microarray data and by predicting the interest rates, we explore nonparametric estimation of additive models with highly correlated covariates. We introduce two novel approaches for estimating the additive components, integration estimation and pooled backfitting estimation. The former is designed for highly correlated covariates, and the latter is useful for nonhighly correlated covariates. Asymptotic normalities of the proposed estimators are established. Simulations are conducted to demonstrate finite sample behaviors of the proposed estimators, and real data examples are given to illustrate the value of the methodology.

This paper introduces an efficient approach to integrating non-local statistics into the higher-order Markov Random Fields (MRFs) framework. Motivated by the observation that many non-local statistics (eg, shape priors, color distributions) can usually be represented by a small number of parameters, we reformulate the higher-order MRF model by introducing additional latent variables to represent the intrinsic dimensions of the higher-order cliques. The resulting new model, called NC-MRF, not only provides the flexibility in representing the configurations of higher-order cliques, but also automatically decomposes the energy function into less coupled terms, allowing us to design an efficient algorithmic framework for maximum a posteriori (MAP) inference. Based on this novel modeling/inference framework, we achieve state-of-the-art solutions to the challenging problems of class-specific image segmentation and template-based 3D facial expression tracking, which demonstrate the potential of our approach.

Additive regression models have turned out to be a useful statistical tool in analyses of high-dimensional data sets. Recently, an estimator of additive components has been introduced by Linton and Nielsen which is based on marginal integration. The explicit definition of this estimator makes possible a fast computation and allows an asymptotic distribution theory. In this paper an asymptotic treatment of this estimate is offered for several models. A modification of this procedure is introduced. We consider weighted marginal integration for local linear fits and we show that this estimate has the following advantages.

In this chapter, we give a selective review of the nonparametric modeling methods using Cox's type of models in survival analysis. We first introduce Cox's model (Cox 1972) and then study its variants in the direction of smoothing. The model fitting, variable selection, and hypothesis testing problems are addressed. A number of topics worthy of further study are given throughout this chapter.