Askewing'method is shown to effectively reduce the order of bias of locally parametric estimators, and at the same time retain positivity properties. The technique involves first calculating the usual locally parametric approximation in the neighbourhood of a point x'that is a short distance from the place x where the we wish to estimate the density, and then evaluating this approximation at x. By way of comparison, the usual locally parametric approach takes x'= x. In our construction, x'-x depends in a very simple way on the bandwidth and the kernel, and not at all on the unknown density. Using skewing in this simple form reduces the order of bias from the square to the cube of bandwidth; and taking the average of two estimators computed in this way further reduces bias, to the fourth power of bandwidth. On the other hand, variance increases only by at most a moderate constant factor.

Generalized likelihood ratio statistics have been proposed in Fan, Zhang and Zhang [Ann. Statist. 29 (2001) 153193] as a generally applicable method for testing nonparametric hypotheses about nonparametric functions. The likelihood ratio statistics are constructed based on the assumption that the distributions of stochastic errors are in a certain parametric family. We extend their work to the case where the error distribution is completely unspecified via newly proposed sieve empirical likelihood ratio (SELR) tests. The approach is also applied to test conditional estimating equations on the distributions of stochastic errors. It is shown that the proposed SELR statistics follow asymptotically rescaled 2-distributions, with the scale constants and the degrees of freedom being independent of the nuisance parameters. This demonstrates that the Wilks phenomenon observed in Fan, Zhang and Zhang [Ann. Statist. 29

In this chapter, we give a selective review of the nonparametric modeling methods using Cox's type of models in survival analysis. We first introduce Cox's model (Cox 1972) and then study its variants in the direction of smoothing. The model fitting, variable selection, and hypothesis testing problems are addressed. A number of topics worthy of further study are given throughout this chapter.

In the event-related functional magnetic resonance imaging (fMRI) data analysis, there is an extensive interest in accurately and robustly estimating the hemodynamic response function (HRF) and its associated statistics (eg, the magnitude and duration of the activation). Most methods to date are developed in the time domain and they have utilized almost exclusively the temporal information of fMRI data without accounting for the spatial information. The aim of this paper is to develop a multiscale adaptive smoothing model (MASM) in the frequency domain by integrating the spatial and temporal information to adaptively and accurately estimate HRFs pertaining to each stimulus sequence across all voxels in a three-dimensional (3D) volume. We use two sets of simulation studies and a real data set to examine the finite sample performance of MASM in estimating HRFs. Our real and simulated data analyses confirm

Kernel density estimates are frequently used, based on a second order kernel. Thus, the bias inherent to the estimates has an order of O(<i>h</i>²_<i>n</i>). In this note, a method of correcting the bias in the kernel density estimates is provided, which reduces the bias to a smaller order. Effectively, this method produces a higher order kernel based on a second order kernel. For a kernel function <i>K</i>, the functions W_k(x)=^k-1₁₌₀(^k_l+1)x^lK^(l)(x)/l! and [1/<i>K</i>^{(<i>k</i> 1)}(<i>x</i>)/<i>x</i> d <i>x</i>]<i>K</i>^{(<i>k</i> 1)}(<i>x</i>)/<i>x</i> are kernels of order <i>k</i>, under some mild conditions.