We describe local mirror symmetry from a mathematical point of view and make several A-model calculations using the mirror principle (localization). Our results agree with B-model computations from solutions of Picard-Fuchs differential equations constructed form the local geometry near a Fano surface within a Calabi-Yau manifold. We interpret the Gromov-Witten-type numbers from an enumerative point of view. We also describe the geometry of singular surfaces and show how the local invariants of singular surfaces agree with the smooth cases when they occur as complete intersections.

There is an unmet medical need to identify neuroimaging biomarkers that allow us to accurately diagnose and monitor Alzheimer's disease (AD) at its very early stages and to assess the response to AD-modifying therapies. To a certain extent, volumetric and functional magnetic resonance imaging (fMRI) studies can detect changes in structure, cerebral blood flow, and blood oxygenation that distinguish AD and mild cognitive impairment (MCI) subjects from healthy control (HC) subjects. However, it has been challenging to use fully automated MRI analytic methods to identify potential AD neuroimaging biomarkers. We have thus proposed a method based on independent component analysis (ICA) for studying potential AD-related MR image features that can be coupled with the use of support vector machine (SVM) for classifying scans into categories of AD, MCI, and HC subjects. The MRI data were selected from

We study the homogenization of a stationary conductivity problem in a random heterogeneous medium with highly oscillating conductivity coefficients and an ensemble of simply closed conductivity resistant membranes. This medium is randomly deformed and then rescaled from a periodic one with periodic membranes, in a manner similar to the random medium proposed by Blanc, Le Bris, and Lions (2006). Across the membranes, the flux is continuous but the potential field itself undergoes a jump of Robin-type. We prove that, for almost all realizations of the random deformation, as the small scale of variations of the medium goes to zero, the random conductivity problem is well approximated by that of an effective medium which has deterministic and constant coefficients and contains no membrane. The effective coefficients are explicitly represented. One of our main contributions is to provide a solution to the associated auxiliary problem that is posed on the whole space with infinitely many interfaces, a setting that is out of the standard stationary ergodic framework.

We define the counting of holomorphic cylinders in log Calabi-Yau surfaces. Although we start with a complex log Calabi-Yau surface, the counting is achieved by applying methods from non-archimedean geometry. This gives rise to new geometric invariants. Moreover, we prove that the counting satisfies a property of symmetry. Explicit calculations are given for a del Pezzo surface in detail, which verify the conjectured wall-crossing formula for the focus-focus singularity. Our holomorphic cylinders are expected to give a geometric understanding of the combinatorial notion of broken line by Gross, Hacking, Keel and Siebert. Our tools include Berkovich spaces, tropical geometry, Gromov-Witten theory and the GAGA theorem for non-archimedean analytic stacks.

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