We study the isoperimetric structure of asymptotically flat Riemannian 3-manifolds (M, g) that are C0-asymptotic to Schwarzschild of mass m > 0. Refining an argument due to H. Bray, we obtain an effective volume comparison theorem in Schwarzschild. We use it to show that isoperimetric regions exist in (M, g) for all sufficiently large volumes, and that they are close to centered coordinate spheres. This implies that the volume-preserving stable constant mean curvature spheres constructed by G. Huisken and S.-T. Yau as well as R. Ye as perturbations of large centered coordinate spheres minimize area among all competing surfaces that enclose the same volume. This confirms a conjecture of H. Bray. Our results are consistent with the uniqueness results for volumepreserving stable constant mean curvature surfaces in initial data sets obtained by G. Huisken and S.-T. Yau and strengthened by J. Qing and G. Tian. The additional hypotheses that the surfaces be spherical and far out in the asymptotic region in their results are not necessary in our work.

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Given a Lagrangian sphere in a symplectic 4–manifold $(M, \omega)$ with $b^{+}=1$, we find embedded symplectic surfaces intersecting it minimally. When the Kodaira dimension  $\kappa$ of $(M,\omega)$ is $-\infty$, this minimal intersection property turns out to be very powerful for both the uniqueness and existence problems of Lagrangian spheres. On the uniqueness side, for a symplectic rational manifold and any class which is not characteristic, we show that homologous Lagrangian spheres are smoothly isotopic, and when the Euler number is less than 8, we generalize Hind and Evans’ Hamiltonian uniqueness in the monotone case. On the existence side, when  $\kappa=-\infty$, we give a characterization of classes represented by Lagrangian spheres, which enables us to describe the non-Torelli part of the symplectic mapping class group.

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In this paper, we investigate the space of certain weak stability conditions on the triangulated category of D0-D2-D6 bound states on a smooth projective Calabi-Yau 3-fold. In the case of a quintic 3-fold, the resulting space is interpreted as a universal covering space of an infinitesimal neighborhood of the conifold point in the stringy K¨ahler moduli space. We then associate the DT type invariants counting semistable objects, which give new curve counting invariants on Calabi-Yau 3-folds. We also investigate the wall-crossing formula of our invariants and their interplay with the Seidel-Thomas twist.