We show that the transition probability of the Markov chain ($G$($i$,1),...,$G$($i$,$n$))_{$i$≥1}, where the$G$($i$,$j$)’s are certain directed last-passage times, is given by a determinant of a special form. An analogous formula has recently been obtained by Warren in a Brownian motion model. Furthermore we demonstrate that this formula leads to the Meixner ensemble when we compute the distribution function for$G$($m$,$n$). We also obtain the Fredholm determinant representation of this distribution, where the kernel has a double contour integral representation.