To study arithmetic structures of natural numbers, we introduce a notion of entropy of arithmetic functions, called anqie entropy. This entropy possesses some crucial properties common to both Shannon's and Kolmogorov's entropies. We show that all arithmetic functions with zero anqie entropy form a C*-algebra. Its maximal ideal space defines our arithmetic compactification of natural numbers, which is totally disconnected but not extremely disconnected. We also compute the $K$-groups of the space of all continuous functions on the arithmetic compactification. As an application, we show that any topological dynamical system with topological entropy $\lambda$, can be approximated by symbolic dynamical systems with entropy less than or equal to $\lambda$.

We study the general problem of equidistribution of expanding translates of an analytic curve by an algebraic diagonal flow on the homogeneous space of a semisimple algebraic group G. We define two families of algebraic subvarieties of the associated partial flag variety, which give the obstructions to non-divergence and equidistribution. We apply this to prove that for Lebesgue almost every point on an analytic curve in the space of m × n real matrices whose image is not contained in any subvariety coming from these two families, Dirichlet’s theorem on simultaneous Diophantine approximation cannot be improved. The proof combines geometric invariant theory, Ratner’s theorem on measure rigidity for unipotent flows, and linearization technique.

Firstly, a formal correspondence is established between the CamassaHolm (CH) equation and a two-component modified CH (or called SQQ) equation according to the method of <i>moment modification</i> for multipeakon formulae. Secondly, based on the generalized nonisospectral CH equation in Chang et al. (2014) [14] and the interlacing multipeakons of the two-component modified CH equation in Chang et al. (2016) [15], we propose a new generalized two-component modified CH equation with two parameters, which possesses a nonisospectral Lax pair. The proposed equation still admits multipeakon solutions of explicit and closed form. Sufficient conditions for global existence of solutions are given and two concrete examples with certain interesting phenomenon are presented. Last of all, as a by-product, a generalized nonisospectral modified CH equation is deduced, together with its Lax pair.

For a random walk on a finitely generated group G we obtain a generalization of a classical inequality of Ancona. We deduce as a corollary that the identity map on G extends to a continuous equivariant surjection from the Martin boundary to the Floyd boundary, with preimages of conical points being singletons. This provides new results for Martin compactifications of relatively hyperbolic groups.

Modeling cell differentiation from omics data is an essential problem in systems biology research. Although many algorithms have been established to analyze scRNA-seq data, approaches to infer the pseudo-time of cells or quantify their potency have not yet been satisfactorily solved. Here, we propose the Landscape of Differentiation Dynamics (LDD) method, which calculates cell potentials and constructs their differentiation landscape by a continuous birth-death process from scRNA-seq data. From the viewpoint of stochastic dynamics, we exploited the features of the differentiation process and quantified the differentiation landscape based on the source-sink diffusion process. In comparison with other scRNA-seq methods in seven benchmark datasets, we found that LDD could accurately and efficiently build the evolution tree of cells with pseudo-time, in particular quantifying their differentiation landscape in terms of potency. This study provides not only a computational tool to quantify cell potency or the Waddington potential landscape based on scRNA-seq data, but also novel insights to understand the cell differentiation process from a dynamic perspective.