A bandwidth selection method is proposed for local linear regression. Our approach is to combine the ideas of optimal bandwidth selection of Hall et al.(1991) in kernel density estimation, and use of direct bias and variance in Fan and Gijbels (1995) for local linear regression. We show that the bandwidth selector has an optimal relative rate of convergence of n-1/2 with n the sample size.

Deconvolution problems arise in a variety of situations in statistics. An interesting problem is to estimate the density f of a random variable X based on n i.i.d. observations from Y = X + , where is a measurement error with a known distribution. In this paper, the effect of errors in variables of nonparametric deconvolution is examined. Insights are gained by showing that the difficulty of deconvolution depends on the smoothness of error distributions: the smoother, the harder. In fact, there are two types of optimal rates of convergence according to whether the error distribution is ordinary smooth or supersmooth. It is shown that optimal rates of convergence can be achieved by deconvolution kernel density estimators.

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A variable screening procedure via correlation learning was proposed by Fan and Lv (2008) to reduce dimensionality in sparse ultra-high-dimensional models. Even when the true model is linear, the marginal regression can be highly nonlinear. To address this issue, we further extend the correlation learning to marginal nonparametric learning. Our nonparametric independence screening (NIS) is a specific type of sure independence screening. We propose several closely related variable screening procedures. We show that with general nonparametric models, under some mild technical conditions, the proposed independence screening methods have a sure screening property. The extent to which the dimensionality can be reduced by independence screening is also explicitly quantified. As a methodological extension, we also propose a data-driven thresholding and an iterative nonparametric independence

Comparing DNA or protein sequences plays an important role in the functional analysis of genomes. Despite many methods available for sequences comparison, few methods retain the information content of sequences. We propose a new approach, the Yau-Hausdorff method, which considers all translations and rotations when seeking the best match of graphical curves of DNA or protein sequences. The complexity of this method is lower than that of any other two dimensional minimum Hausdorff algorithm. The Yau-Hausdorff method can be used for measuring the similarity of DNA sequences based on two important tools: the Yau-Hausdorff distance and graphical representation of DNA sequences. The graphical representations of DNA sequences conserve all sequence information and the Yau-Hausdorff distance is mathematically proved as a true metric. Therefore, the proposed distance can preciously measure the similarity of DNA sequences. The phylogenetic analyses of DNA sequences by the Yau-Hausdorff distance show the accuracy and stability of our approach in similarity comparison of DNA or protein sequences. This study demonstrates that Yau-Hausdorff distance is a natural metric for DNA and protein sequences with high level of stability. The approach can be also applied to similarity analysis of protein sequences by graphic representations, as well as general two dimensional shape matching.