Large-scale multiple testing with correlated and heavy-tailed data arises in a wide range of research areas from genomics, medical imaging to finance. Conventional methods for estimating the false discovery proportion (FDP) often ignore the effect of heavy-tailedness and the dependence structure among test statistics, and thus may lead to inefficient or even inconsistent estimation. Also, the commonly imposed joint normality assumption is arguably too stringent for many applications. To address these challenges, in this article we propose a factor-adjusted robust multiple testing (FarmTest) procedure for large-scale simultaneous inference with control of the FDP. We demonstrate that robust factor adjustments are extremely important in both controlling the FDP and improving the power. We identify general conditions under which the proposed method produces consistent estimate of the FDP. As a byproduct that is

When people in a society want to make inference about some parameter, each person would potentially want to use data collected by other people. Information (data) exchange in social contexts is usually costly, so to make sound statistical decisions, people need to compromise between benefits and costs of information acquisition. Conflicts of interests and coordination will arise. Classical statistics does not consider peoples interaction in the data collection process. To address this ignorance, this work explores multi-agent Bayesian inference problems with a game theoretic social network model. Bearing our interest in aggregate inference at the societal level, we propose a new concept finite population learning to address whether with high probability, a large fraction of people can make good inferences. Serving as a foundation, this concept enables us to study the long run trend of aggregate inference quality as population grows.

Semiparametric regression models are very useful for longitudinal data analysis. The complexity of semiparametric models and the structure of longitudinal data pose new challenges to parametric inferences and model selection that frequently arise from longitudinal data analysis. In this article, two new approaches are proposed for estimating the regression coefficients in a semiparametric model. The asymptotic normality of the resulting estimators is established. An innovative class of variable selection procedures is proposed to select significant variables in the semiparametric models. The proposed procedures are distinguished from others in that they simultaneously select significant variables and estimate unknown parameters. Rates of convergence of the resulting estimators are established. With a proper choice of regularization parameters and penalty functions, the proposed variable selection procedures

The problem of estimating the density function and the regression function involving errors-in-variables in time series is considered. Under appropriate conditions, it is shown that the rates obtained in Fan (1991), Fan and Truong (1990) are also achievable in the context of dependent observations. Consequently, the results presented here extend our previous results for cross-sectional data to the longitudinal ones. oAbbreviated title. Measurement Errors in Time Series AMS 1980 subject classification. Primary 62G20. Secondary 62G05, 62J99.

No abstract uploaded!