Recently a computational-based experimental design strategy called rerandomization has been proposed as an alternative or complement to traditional blocked designs. The idea of rerandomization is to remove, from consideration, those allocations with large imbalances in observed covariates according to a balance criterion, and then randomize within the set of acceptable allocations. Based on the Mahalanobis distance criterion for balancing the covariates, we show that asymptotic inference to the population, from which the units in the sample are randomly drawn, is possible using only the set of best, or ‘optimal’, allocations. Finally, we show that for the optimal and near optimal designs, the quite complex asymptotic sampling distribution derived by Li et al. (2018), is well approximated by a normal distribution.

For multiple index models, it has recently been shown that the sliced inverse regression (SIR) is consistent for estimating the sufficient dimension reduction (SDR) subspace if and only if the dimension p and sample size n satisfies that ρ=limp/n=0. Thus, when p is of the same or a higher order of n, additional assumptions such as sparsity have to be imposed in order to ensure consistency for SIR. By constructing artificial response variables made up from top eigenvectors of the estimated conditional covariance matrix, \widehat{var(𝔼[x|y])}, we introduce a simple Lasso regression method to obtain an estimate of the SDR subspace. The resulting algorithm, Lasso-SIR, is shown to be consistent and achieve the optimal convergence rate under certain sparsity conditions when p is of order o(n^2λ^2) where λ is the generalized signal noise ratio. We also demonstrate the superior performance of Lasso-SIR compared with existing approaches via extensive numerical studies and several real data examples.

In deconvolution in R^d, d≥1, with mixing density p(∈\mathscr{P}) and kernel h, the mixture density f_p(∈\mathscr{F}_p) is estimated with MDE f_{\hat{p}n}, having upper L1-error rate, an, in probability or in risk; \hat{p}_n∈\mathscr{P}. In one application, \mathscr{P} consists of L1-separable densities in R with differences changing sign at most J times and h(x−y) Totally Positive. When h is known and p is \tilde{q}-smooth, vanishing outside a compact in R^d, plug-in upper bounds are provided for the L2-error rate of \hat{p}_n and its [s]-th mixed partial derivative \hat{p}^{(s)}_n, via ∥f_{\hat{p}_n}−f_p∥_1, with rates (log a^{−1}_n)^{−N_1} and a^{N_2}_n, respectively, for h super-smooth and smooth; \tilde{q}∈R^+, [s] ≤ \tilde{q}, d≥1, N_1>0, N_2>0. For a_n ∼ (logn)^ζ⋅(n^{−δ}), the former rate is optimal for any δ>0 and the latter misses the optimal by the factor (logn)^ξ when δ=.5; ζ>0, ξ>0. N_1 and N_2 appear in optimal rates and lower error and risk bounds in the deconvolution literature.

Many statistical models seek relationship between variables via subspaces of reduced dimensions. For instance, in factor models, variables are roughly distributed around a low dimensional subspace determined by the loading matrix; in mixed linear regression models, the coefficient vectors for different mixtures form a subspace that captures all regression functions; in multiple index models, the effect of covariates is summarized by the effective dimension reduction space.

Double-blind randomized controlled trials are traditionally seen as the gold standard for causal inferences as the difference-in-means estimator is an unbiased estimator of the average treatment effect in the experiment. The fact that this estimator is unbiased over all possible randomizations does not, however, mean that any given estimate is close to the true treatment effect. Similarly, while predetermined covariates will be balanced between treatment and control groups on average, large imbalances may be observed in a given experiment and the researcher may therefore want to condition on such covariates using linear regression. This article studies the theoretical properties of both the difference-in-means and OLS estimators conditional on observed differences in covariates. By deriving the statistical properties of the conditional estimators, we can establish guidance for how to deal with covariate imbalances.