Given a Lagrangian sphere in a symplectic 4–manifold $(M, \omega)$ with $b^{+}=1$, we find embedded symplectic surfaces intersecting it minimally. When the Kodaira dimension  $\kappa$ of $(M,\omega)$ is $-\infty$, this minimal intersection property turns out to be very powerful for both the uniqueness and existence problems of Lagrangian spheres. On the uniqueness side, for a symplectic rational manifold and any class which is not characteristic, we show that homologous Lagrangian spheres are smoothly isotopic, and when the Euler number is less than 8, we generalize Hind and Evans’ Hamiltonian uniqueness in the monotone case. On the existence side, when  $\kappa=-\infty$, we give a characterization of classes represented by Lagrangian spheres, which enables us to describe the non-Torelli part of the symplectic mapping class group.

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Recently, Tsai-Tseng-Yau constructed new invariants of symplectic manifolds: a sequence of A-infinity algebras built of differential forms on the symplectic manifold. We show that these symplectic A-infinity algebras have a simple topological interpretation. Namely, when the cohomology class of the symplectic form is integral, these A-infinity algebras are equivalent to the standard de Rham differential graded algebra on certain odd dimensional sphere bundles over the symplectic manifold. From this equivalence, we deduce for a closed symplectic manifold that Tsai-Tseng-Yau's symplectic A-infinity algebras satisfy the Calabi-Yau property, and importantly, that they can be used to define an intersection theory for coisotropic/isotropic chains. We further demonstrate that these symplectic A-infinity algebras satisfy several functorial properties and lay the groundwork for addressing Weinstein functoriality and invariance in the smooth category.

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