Let V be a hypersurface with an isolated singularity at the origin defined
by the holomorphic function f : (Cn , 0) → (C, 0). The Yau algebra L(V ) is defined to
be the Lie algebra of derivations of the moduli algebra A(V ) := On/(f, ∂f , · · · , ∂f ), ∂x1 ∂xn
i.e., L(V ) = Der(A(V ), A(V )) and plays an important role in singularity theory. It is known that L(V ) is a finite dimensional Lie algebra and its dimension λ(V ) is called Yau number. In this article, we generalize the Yau algebra and introduce a new series of k-th Yau algebras Lk(V) which are defined to be the Lie algebras of derivations of the moduli algebras Ak(V) = On/(f,mkJ(f)),k ≥ 0, i.e., Lk(V) = Der(Ak(V),Ak(V)) and where m is the maximal ideal of On. In particular, it is Yau algebra when k = 0. The dimension of Lk(V ) is denoted by λk(V ). These numbers i.e., k-th Yau numbers λk(V ), are new numerical analytic invariants of an isolated singularity. In this paper we studied these new series of Lie algebras Lk(V ) and also compute the Lie algebras L1(V ) for fewnomial isolated singularities. We also formulate a sharp upper estimate conjecture for the λk(V ) of weighted homogeneous isolated hypersurface singularities and we prove this conjecture in case of k = 1 for large class of singularities.