Problems of nonparametric ltering arises frequently in engineering and nancial economics. Nonparametric lters often involve some ltering parameters to choose. These parameters can be chosen to optimize the performance locally at each time point or globally over a time interval. In this article, the ltering parameters are chosen via minimizing the prediction error for a large class of lters. Under a general martingale setting, with mild conditions on the time series structure and virtually no assumption on lters, we show that the adaptive lter with ltering parameter chosen by historical data performs nearly as well as the one with the ideal lter in the class, in terms of ltering errors. The theoretical result is also veri ed via intensive simulations. Our approach is also useful for choosing the orders of parametric models such as AR or GARCH processes. It can also be applied to volatility estimation in nancial economics. We illustrate the proposed methods by estimating the volatility of the returns of the S&P500 index and the yields of the three-month Treasury bills.

A uniform approach is introduced to study the existence of measure valued solutions to the homogeneous Boltzmann equation for both hard potential with finite energy, and soft potential with finite or infinite energy, by using Toscani metric. Under the non-angular cutoff assumption on the cross-section, the solutions obtained are shown to be in the Schwartz space in the velocity variable as long as the initial data is not a single Dirac mass without any extra moment condition for hard potential, and with the boundedness on moments of any order for soft potential.

The solvability in Sobolev spaces is proved for divergence form complex-valued higher order parabolic systems in the whole space, on a half-space, and on a Reifenberg flat domain. The leading coefficients are assumed to be merely measurable in one spacial direction and have small mean oscillations in the orthogonal directions on each small cylinder. The directions in which the coefficients are only measurable vary depending on each cylinder. The corresponding elliptic problem is also considered.

Cryo-electron microscopy (cryo-EM) has recently emerged as a powerful tool for obtaining three-dimensional (3D) structures of biological macromolecules in native states. A minimum cryo-EM image data set for deriving a meaningful reconstruction is comprised of thousands of randomly orientated projections of identical particles photographed with a small number of electrons. The computation of 3D structure from 2D projections requires clustering, which aims to enhance the signal to noise ratio in each view by grouping similarly oriented images. Nevertheless, the prevailing clustering techniques are often compromised by three characteristics of cryo-EM data: high noise content, high dimensionality and large number of clusters. Moreover, since clustering requires registering images of similar orientation into the same pixel coordinates by 2D alignment, it is desired that the clustering algorithm can label misaligned images as outliers. Herein, we introduce a clustering algorithm γ-SUP to model the data with a q-Gaussian mixture and adopt the minimum γ-divergence for estimation, and then use a self-updating procedure to obtain the numerical solution. We apply γ-SUP to the cryo-EM images of two benchmark macromolecules, RNA polymerase II and ribosome. In the former case, simulated images were chosen to decouple clustering from alignment to demonstrate γ-SUP is more robust to misalignment outliers than the existing clustering methods used in the cryo-EM community. In the latter case, the clustering of real cryo-EM data by our γ-SUP method eliminates noise in many views to reveal true structure features of ribosome at the projection level.

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