String and particle braiding statistics are examined in a class of topological orders
described by discrete gauge theories with a gauge group $G$ and a 4-cocycle twist $\omega_4$ of $G$'s cohomology group $\mathcal{H}^4(G,\mathbb{R}/\mathbb{Z})$
in 3 dimensional space and 1 dimensional time (3+1D).
We establish the topological spin and the spin-statistics relation for the closed strings, and their multi-string braiding statistics.
The 3+1D twisted gauge theory can be characterized by a representation of a modular transformation group SL$(3,\mathbb{Z})$. We express the SL$(3,\mathbb{Z})$ generators $\mathsf{S}^{xyz}$ and $\mathsf{T}^{xy}$ in terms of the gauge group $G$ and the 4-cocycle $\omega_4$. As we
compactify one of the spatial %3D's
directions $z$ into a compact circle with a gauge flux $b$ inserted,
we can use the generators $\mathsf{S}^{xy}$ and $\mathsf{T}^{xy}$ of an SL$(2,\mathbb{Z})$ subgroup to study the dimensional
reduction of the 3D topological order $\mathcal{C}^{3\text{D}}$ to a direct sum of degenerate states of 2D
topological orders $\mathcal{C}_b^{2\text{D}}$ in different flux $b$ sectors: $\mathcal{C}^{3\text{D}} = \oplus_b \mathcal{C}_b^{2\text{D}}$. The 2D topological orders $\mathcal{C}_b^{2\text{D}}$ are described by 2D gauge theories of the group $G$ twisted by the
3-cocycles $\omega_{3(b)}$, dimensionally reduced from the 4-cocycle $\omega_4$. We show that the SL$(2,\mathbb{Z})$ generators, $\mathsf{S}^{xy}$ and $\mathsf{T}^{xy}$,
fully encode
a particular
type of three-string braiding statistics with a pattern that is the connected sum of two Hopf links. With certain 4-cocycle twists, we discover that, by threading a third string through two-string unlink into three-string Hopf-link configuration, Abelian two-string braiding statistics is promoted to non-Abelian three-string braiding statistics.