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We construct a virus database called VirusDB (http://yaulab.math.tsinghua.edu.cn/VirusDB/) and an online inquiry system to serve people who are interested in viral classification and prediction. The database stores all viral genomes, their corresponding natural vectors, and the classification information of the single/multiple-segmented viral reference sequences downloaded from National Center for Biotechnology Information. The online inquiry system serves the purpose of computing natural vectors and their distances based on submitted genomes, providing an online interface for accessing and using the database for viral classification and prediction, and back-end processes for automatic and manual updating of database content to synchronize with GenBank. Submitted genomes data in FASTA format will be carried out and the prediction results with 5 closest neighbors and their classifications will be returned by email. Considering the one-to-one correspondence between sequence and natural vector, time efficiency, and high accuracy, natural vector is a significant advance compared with alignment methods, which makes VirusDB a useful database in further research.

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In this paper, we develop a three-dimensional parallel solver using the fifth order high-resolution weighted essentially non-oscillatory (WENO) finite difference scheme to perform extensive simulation for three-dimensional gaseousdetonations. A careful study is conducted for the propagation modes of three-dimensional gaseous detonation wave-front structures in a long square duct. The numerical results indicate that, the instability of detonation, overdrive factor, transverse dimension and initial perturbation are the main factors that influence the appearance of spinning detonation.

We consider singular integral operators of the form (a)$Z$_{1}L^{−1}Z_{2}, (b)$Z$_{1}Z_{2}L^{−1}, and (c)$L$^{−1}Z_{1}Z_{2}, where$Z$_{1}and$Z$_{2}are nonzero right-invariant vector fields, and$L$is the$L$^{2}-closure of a canonical Laplacian. The operators (a) are shown to be bounded on$L$^{p}for all$p$∈(1, ∞) and of weak type (1, 1), whereas all of the operators in (b) and (c) are not of weak type ($p, p$) for any$p$∈[1, ∞).