Consider $N$ bosons in a finite box  $ \Lambda = [0,L]^3 \subset R^3$ interacting via a two-body smooth repulsive short range potential. We construct a variational state which gives the following upper bound on the ground state energy per particle $$ \bar{lim|_{\rho \to 0} \bar{lim|_{L \to \infty, N/L^3 \to \rho} ( \ frac{e_0 (\rho) - 4\pi a \rho }{ (4\pi a)^{5/2} (\rho)^{3/2} } ) \le \frac{16}{15 \pi ^2} , $$ where $a$ is the scattering length of the potential. Previously, an upper bound of the form $C16/15\pi^2$ for some constant $C >1$ was obtained in (Erdös et al. in Phys. Rev. A 78:053627, 2008). Our result proves the upper bound of the prediction by Lee and Yang (Phys. Rev. 105(3):1119–1120, 1957) and Lee et al. (Phys. Rev. 106(6):1135–1145, 1957).

Alzheimer's disease (AD) is a no-cure disease that has been frustrating the scientists for many years. Analyzing the disease has become an important but challenging research topic. The shape analysis of the sub-cortical structure of AD patients has been commonly used to understand this disease. In this paper, we assess the feasibility of using shape information on the hippocampal (HP) surfaces to detect some sub-structural changes in AD patients. We propose a quasi-conformal statistical shape analysis model, which allows us to study local regional geometric changes in the HPs amongst normal control (NC) and AD groups. A shape index defined by the quasi-conformality and surface curvatures is used to characterize region-specific shape variations of the HP surfaces. Feature vectors can be extracted for each HPs, with which a classification model can be built using machine learning methods to classify HPs into NC and AD subjects. Experiments have been carried out on 99 normal controls and 41 patients with AD. Results demonstrate that the proposed quasi-conformal based model is effective for classifying HPs into NC and AD groups with high classification accuracy (with highest overall classification accuracy reaching 87.86% in a leave-one-out experiment using the whole dataset).

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Lutwak, Yang and Zhang defined the cone volume functional U over convex polytopes in R^n containing the origin in their interiors, and conjectured that the greatest lower bound on the ratio of this centro-affine invariant U to volume V is attained by parallelotopes. In this paper, we give affirmative answers to the conjecture in R^2 and R^3. Some new sharp inequalities characterizing parallelotopes in Rn are established. Moreover, a simplified proof for the conjecture restricted to the class of origin-symmetric convex polytopes in Rn is provided.

We show that the recently proposed weak gravity conjecture\cite{AMNV0601} can be extended to a class of scalar field theories. Taking gravity into account, we find an upper bound on the gravity interaction strength, expressed in terms of scalar coupling parameters. This conjecture is supported by some two-dimensional models and noncommutative field theories.