In this chapter, we give a selective review of the nonparametric modeling methods using Cox's type of models in survival analysis. We first introduce Cox's model (Cox 1972) and then study its variants in the direction of smoothing. The model fitting, variable selection, and hypothesis testing problems are addressed. A number of topics worthy of further study are given throughout this chapter.

In this paper, we study robust covariance estimation under the approximate factor model with observed factors. We propose a novel framework to first estimate the initial joint covariance matrix of the observed data and the factors, and then use it to recover the covariance matrix of the observed data. We prove that once the initial matrix estimator is good enough to maintain the element-wise optimal rate, the whole procedure will generate an estimated covariance with desired properties. For data with bounded fourth moments, we propose to use adaptive Huber loss minimization to give the initial joint covariance estimation. This approach is applicable to a much wider class of distributions, beyond sub-Gaussian and elliptical distributions. We also present an asymptotic result for adaptive Hubers M-estimator with a diverging parameter. The conclusions are demonstrated by extensive simulations and real data analysis.

We present a new estimator for precision matrix in high dimensional Gaussian graphical models. At the core of the proposed estimator is a collection of node-wise linear regression with nonconvex penalty. In contrast to existing estimators for Gaussian graphical models with O (s log d/n) estimation error bound in terms of spectral norm, where s is the maximum degree of a graph, the proposed estimator could attain O (s/ n+ log d/n) spectral norm based convergence rate in the best case, and it is no worse than exiting estimators in general. In addition, our proposed estimator enjoys the oracle property under a milder condition than existing estimators. We show through extensive experiments on both synthetic and real datasets that our estimator outperforms the state-of-the-art estimators.

Motivated by normalizing DNA microarray data and by predicting the interest rates, we explore nonparametric estimation of additive models with highly correlated covariates. We introduce two novel approaches for estimating the additive components, integration estimation and pooled backfitting estimation. The former is designed for highly correlated covariates, and the latter is useful for nonhighly correlated covariates. Asymptotic normalities of the proposed estimators are established. Simulations are conducted to demonstrate finite sample behaviors of the proposed estimators, and real data examples are given to illustrate the value of the methodology.

High-dimensional statistical tests often ignore correlations to gain simplicity and stability leading to null distributions that depend on functionals of correlation matrices such as their Frobenius norm and other r norms. Motivated by the computation of critical values of such tests, we investigate the difficulty of estimation the functionals of sparse correlation matrices. Specifically, we show that simple plug-in procedures based on thresholded estimators of correlation matrices are sparsity-adaptive and minimax optimal over a large class of correlation matrices. Akin to previous results on functional estimation, the minimax rates exhibit an elbow phenomenon. Our results are further illustrated in simulated data as well as an empirical study of data arising in financial econometrics.