We will show that for any noncompact arithmetic hyperbolic m-manifold with m>3, and any compact arithmetic hyperbolic m-manifold with m > 4 that is not a 7-dimensional one defined by octonions, its fundamental group is not locally extended residually finite (LERF). The main ingredient in the proof is a study on abelian amalgamations of hyperbolic 3-manifold groups. We will also show that a compact orientable irreducible 3-manifold with empty or tori boundary supports a geometric structure if and only if its fundamental group is LERF.

We quantized the full Einstein equations in a globally hyperbolic spacetime $N=N^{n+1}$, $n\ge 3$, and found solutions of the resulting hyperbolic equation in a fiber bundle $E$ which can be expressed as a product of spatial eigenfunctions (eigendistributions) and temporal eigenfunctions. The spatial eigenfunctions form a basis in an appropriate Hilbert space while the temporal eigenfunctions are solutions to a second order ordinary differential equation in $\R[]_+$. In case $n\ge 17$ and provided the cosmological constant $\Lam$ is negative the temporal eigenfunctions are eigenfunctions of a self-adjoint operator $\hat H_0$ such that the eigenvalues are countable and the eigenfunctions form an orthonormal basis of a Hilbert space.

The free-living SAR11 clade is a globally abundant group of oceanic Alphaproteobacteria, with small genome sizes and rich genomic A+T content. However, the taxonomy of SAR11 has become controversial recently. Some researchers argue that the position of SAR11 is a sister group to Rickettsiales. Other researchers advocate that SAR11 is located within free-living lineages of Alphaproteobacteria. Here, we use the natural vector representation method to identify the evolutionary origin of the SAR11 clade. This alignment-free method does not depend on any model assumptions. With this approach, the correspondence between proteome sequences and their natural vectors is one-to-one. After fixing a set of proteins, each bacterium is represented by a set of vectors. The Hausdorff distance is then used to compute the dissimilarity distance between two bacteria. The phylogenetic tree can be reconstructed based on these distances. Using our method, we systematically analyze four data sets of alphaproteobacterial proteomes in order to reconstruct the phylogeny of Alphaproteobacteria. From this we can see that the phylogenetic position of the SAR11 group is within a group of other free-living lineages of Alphaproteobacteria.

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