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We study a robust and efficient eigensolver for computing a few smallest positive eigenvalues of the three-dimensional Maxwell’s transmission eigenvalue problem. The discretized governing equations by the Nedelec edge element result in a large-scale quadratic eigenvalue problem (QEP) for which the spectrum contains many zero eigenvalues and the coefficient matrices consist of patterns in the matrix form XY^{−1}Z, both of which prevent existing eigenvalue solvers from being efficient. To remedy these difficulties, we rewrite the QEP as a particular nonlinear eigenvalue problem and develop a secant-type iteration, together with an indefinite locally optimal block preconditioned conjugate gradient method (LOBPCG), to sequentially compute the desired positive eigenvalues. Furthermore, we propose a novel method to solve the linear systems in each iteration of LOBPCG. Intensive numerical experiments show that our proposed method is robust, although the desired real eigenvalues are surrounded by complex eigenvalues.

We propose a derived version of non-archimedean analytic geometry. Intuitively, a derived non-archimedean analytic space consists of an ordinary non-archimedean analytic space equipped with a sheaf of derived rings. Such a naive definition turns out to be insufficient. In this paper, we resort to the theory of pregeometries and structured topoi introduced by Jacob Lurie. We prove the following three fundamental properties of derived non-archimedean analytic spaces: (1) The category of ordinary non-archimedean analytic spaces embeds fully faithfully into the ∞-category of derived non-archimedean analytic spaces. (2) The ∞-category of derived non-archimedean analytic spaces admits fiber products. (3) The ∞-category of higher non-archimedean analytic Deligne-Mumford stacks embeds fully faithfully into the ∞-category of derived non-archimedean analytic spaces. The essential image of this embedding is spanned by n-localic discrete derived non-archimedean analytic spaces. We will further develop the theory of derived non-archimedean analytic geometry in our subsequent works. Our motivations mainly come from intersection theory, enumerative geometry and mirror symmetry.

There is an unmet medical need to identify neuroimaging biomarkers that is able to accurately diagnose and monitor Alzheimer's disease (AD) at very early stages and assess the response to AD-modifying therapies. To a certain extent, volumetric and functional magnetic resonance imaging (fMRI) studies can detect changes in structure, cerebral blood flow and blood oxygenation that are able to distinguish AD and mild cognitive impairment (MCI) subjects from normal controls. However, it has been challenging to use fully automated MRI analytic methods to identify potential AD neuroimaging biomarkers. We have thus proposed a method based on independent component analysis (ICA), for studying potential AD-related MR image features, coupled with the use of support vector machine (SVM) for classifying scans into categories of AD, MCI, and normal control (NC) subjects. The MRI data were selected from Open Access Series of Imaging Studies (OASIS) and the Alzheimer's Disease Neuroimaging Initiative (ADNI) databases. The experimental results showed that our ICA-based method can differentiate AD and MCI subjects from normal controls, although further methodological improvement in the analytic method and inclusion of additional variables may be required for optimal classification.

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