To understand the new physics and richness of quantum many-body system phenomena is one of the stimuli driving the condensed matter community forward. Importantly, the new insights and solutions for condensed matter theory sometimes come from the developed and developing knowledge of high energy theory, mathematical and particle physics, which is also true the other way around: Condensed matter physics has been providing crucial hints and playgrounds for the fundamental laws of high energy physics. In this thesis, we explore the aspects of symmetry, topology and anomalies in quantum matter with entanglement from both condensed matter and high energy theory viewpoints. The focus of our research is on the gapped many-body quantum systems including symmetry-protected topological states (SPTs) and topologically ordered states (TOs). We first explore the ground state structures of SPTs and TOs: the former can be symmetry twisted and the latter has robust degeneracy. The Berry phases generated by transporting and overlapping ground state sectors potentially provide universal topological invariants that fully characterize the SPTs and TOs. This framework provides us the aspects of symmetry and topology. We establish a field theory representation of SPT invariants in any dimension to uncover group cohomology classification and beyond — the former for SPTs with gapless boundary gauge anomalies, the latter for SPTs with mixed gauge-gravity anomalies. We study topological orders in 3+1 dimensions such as Dijkgraaf-Witten models, which support multi-string braiding statistics; the resulting patterns may be analyzed by the mathematical theory of knots and links. We explore the aspects of surface anomalies of bulk gapped states from the bulk-edge correspondence: The gauge anomalies of SPTs shed light on the construction of bosonic anomalies including Goldstone-Wilczek type, and also guide us to design a non-perturbative lattice model regularizing the low-energy chiral fermion/gauge theory towards the Standard Model while overcoming the Nielsen-Ninomiya fermion-doubling problem without relying on Ginsparg-Wilson fermions. We conclude by utilizing aspects of both quantum mechanical topology and spacetime topology to derive new formulas analogous to Verlinde’s via geometric-topology surgery. This provides new insights for higher dimensional topological states of matter.

We explore the higher-form generalized global symmetries and higher anomalies based on a generalized cobordism theory. Our cobordism calculation guides us to classify higher anomalies and topological terms for Yang-Mills (YM) gauge theories and sigma models in various dimensions. Some of YM gauge theories can be obtained from dynamically gauging the SU(N) time-reversal symmetric cobordism invariants (SU(N)-generalized topological superconductors/insulators [arXiv:1711.11587]). We elaborate the cases of YM theory with a compact Lie gauge group (such as SU(N) with N=2, 3 and others) particularly in a 4d spacetime. We provide the relevant homotopy and cobordism group calculations of higher classifying spaces, based on mathematical tools of algebraic topology, to support the physics stories.

We hypothesize a new and more complete set of anomalies of certain quantum field theories (QFTs) and then give an eclectic proof. First, we propose a set of 't Hooft anomalies of 2d $\mathbb{CP}^{\mathrm{N}-1}$-sigma models at $\theta=\pi$, with N $=2,3,4$ and others, by enlisting all possible 3d cobordism invariants and selecting the matched terms. Second, we propose a set of 't Hooft higher anomalies of 4d time-reversal symmetric SU(N)-Yang-Mills (YM) gauge theory at $\theta=\pi$, via 5d cobordism invariants (higher symmetry-protected topological states) such that compactifying YM theory on a 2-torus matches the constrained 3d cobordism invariants from sigma models. Based on algebraic/geometric topology, QFT analysis, manifold generator dimensional reduction, condensed matter inputs and additional physics criteria, we derive a correspondence between 5d and 3d new invariants, thus broadly prove a more complete anomaly-matching between 4d YM and 2d $\mathbb{CP}^{\mathrm{N}-1}$ models via a twisted 2-torus reduction, done by taking the Poincar\'e dual of specific cohomology class with $\mathbb{Z}_2$ coefficients. We formulate a higher-symmetry analog of "Lieb-Schultz-Mattis theorem" to constrain the low-energy dynamics.

We formulate a family of spin Topological Quantum Filed Theories (spin-TQFTs) as fermionic generalization of bosonic Dijkgraaf-Witten TQFTs. They are obtained by gauging $G$-equivariant invertible spin-TQFTs, or, in physics language, gauging the interacting fermionic Symmetry Protected Topological states (SPTs) with a finite group $G$ symmetry. We use the fact that the latter are classified by Pontryagin duals to spin-bordism groups of the classifying space $BG$. We also consider unoriented analogs, that is $G$-equivariant invertible pin$^\pm$-TQFTs (fermionic time-reversal-SPTs) and their gauging. We compute these groups for various examples of abelian $G$ using Adams spectral sequence and describe all corresponding TQFTs via certain bordism invariants in dimensions 3, 4, and other. This gives explicit formulas for the partition functions of spin-TQFTs on closed manifolds with possible extended operators inserted. The results also provide explicit classification of 't Hooft anomalies of fermionic QFTs with finite abelian group symmetries in one dimension lower. We construct new anomalous boundary deconfined spin-TQFTs (surface fermionic topological orders). We explore SPT and SET (symmetry enriched topologically ordered) states, and crystalline SPTs protected by space-group (e.g.\ translation $\mathbb{Z}$) or point-group (e.g.\ reflection, inversion or rotation $C_m$) symmetries, via the layer-stacking construction.

Comparing DNA and protein sequence groups plays an important role in biological evolutionary relationship research. Despite many methods available for sequence comparison, only a few can be used for group comparison. In this study, we propose a novel approach using convex hulls. We use statistical information contained within the sequences to represent each sequence as a point in high dimensional space. We find that the points belonging to one biological group are located in a different region of space than points belonging to other biological groups. To be more precise, the convex hull of the points from one group are disjoint from the convex hulls of points from other groups. This finding allows us to do phylogenetic analysis for groups in an efficient way. Five different theorems are presented for checking whether two convex hulls intersect or are disjoint. Test results for datasets related to HRV, HPV, Ebolavirus, PKC and protein phosphatase domains demonstrate that our method performs well and provides a new tool for studying group phylogeny. More significantly, the convex analysis presents a new way to search for sequences belonging to a biological group by examining points within the group’s convex hull.