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In this paper we study the existence assertion of the initial boundary value problem for the equation $\frac{\partial u}{\partial t} = \Delta e^{-\Delta u}$. This problem arises in the mathematical description of the evolution of crystal surfaces. Our investigations reveal that the exponent in the equation can have a singular part in the sense of the Lebesgue decomposition theorem, and the exponential nonlinearity somehow “cancels” it out. The net result is that we obtain a solution $u$ that satisfies the equation and the initial boundary conditions in the almost everywhere (a.e.) sense.

We show existence and uniqueness of solutions to the Monge-Ampere equation on compact almost complex manifolds with non-integrable almost complex structure.

Tumor growth and metastasis require that tumor cells must have either the potential to shift genetically or epigenetically between proliferative and invasive phenotypes or both phenotypes simultaneously. In the present study, we demonstrated that neuroblastoma growth and invasion were distinct processes that were carried out by proliferative and invasive phenotypes of tumor cells, respectively. Two subpopulations from human neuroblastoma cell line were isolated: highly invasive (HI) cells and low-invasive (LI) cells. HI and LI cells had different proliferative rate and metastatic ability <i>in vitro</i> and <i>in vivo</i> . In addition, they had distinct activated signal pathways and sensitivities to chemotherapy drugs. Affymetrix microarray and quantitative reverse transcriptasepolymerase chain reaction revealed that visinin-like protein-1 (VSNL-1) mRNA in HI cells was significantly higher than

We survey the theory of complex manifolds that are related to Riemann surface, Hodge theory, Chern class, Kodaira embedding and HirzebruchRiemannRoch, and some modern development of uniformization theorems, KhlerEinstein metric and the theory of DonaldsonUhlenbeckYau on Hermitian YangMills connections. We emphasize mathematical ideas related to physics. At the end, we identify possible future research directions and raise some important open questions.