In 1979, G. Parisi predicted a variational formula for the thermodynamic limit of the free energy in the Sherrington-Kirkpatrick model and described the role played by its minimizer. This formula was verified in the seminal work of Talagrand and later generalized to the mixed p-spin models by Panchenko. In this paper, we prove that the minimizer in Parisi's formula is unique at any temperature and external field by establishing the strict convexity of the Parisi functional.