We develop a global Poincar\'e residue formula to study period integrals of families of complex manifolds. For any compact complex manifold X equipped with a linear system V ∗ of generically smooth CY hypersurfaces, the formula expresses period integrals in terms of a canonical global meromorphic top form on X . Two important ingredients of our construction are the notion of a CY principal bundle, and a classification of such rank one bundles. We also generalize our construction to CY and general type complete intersections. When X is an algebraic manifold having a sufficiently large automorphism group G and V ∗ is a linear representation of G , we construct a holonomic D-module that governs the period integrals. The construction is based in part on the theory of tautological systems we have developed in the paper \cite{LSY1}, joint with R. Song. The approach allows us to explicitly describe a Picard-Fuchs type system for complete intersection varieties of general types, as well as CY, in any Fano variety, and in a homogeneous space in particular. In addition, the approach provides a new perspective of old examples such as CY complete intersections in a toric variety or partial flag variety.

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Given a Lagrangian sphere in a symplectic 4–manifold $(M, \omega)$ with $b^{+}=1$, we find embedded symplectic surfaces intersecting it minimally. When the Kodaira dimension  $\kappa$ of $(M,\omega)$ is $-\infty$, this minimal intersection property turns out to be very powerful for both the uniqueness and existence problems of Lagrangian spheres. On the uniqueness side, for a symplectic rational manifold and any class which is not characteristic, we show that homologous Lagrangian spheres are smoothly isotopic, and when the Euler number is less than 8, we generalize Hind and Evans’ Hamiltonian uniqueness in the monotone case. On the existence side, when  $\kappa=-\infty$, we give a characterization of classes represented by Lagrangian spheres, which enables us to describe the non-Torelli part of the symplectic mapping class group.